Afghanistan's relationship with Pakistan is becoming increasingly strained, with the country threatening Tuesday to boycott a series of upcoming meetings about economic cooperation and coordinated assistance across the border and the cabinet issuing a statement that faulted Pakistan for being the "biggest exporter of terrorism and extremism to the world."

The heightened political stress, in a region where US bases have come under attack and militant activity has increased steadily since May, prompted presidential candidates Sens. Barack Obama and John McCain to address their plans for the war in Afghanistan during separate talks on foreign policy.

The boycott warning follows accusations by Afghan President Hamid Karzai that the Pakistani intelligence agency, Inter Services Intelligence (ISI), has been masterminding terrorist attacks in Afghanistan, reports CBS News.

The cabinet implicated Pakistan's spy agency in a string of recent attacks, including the Kandahar jailbreak, the beheading of Afghans in the Bajaur and Waziristan provinces of Pakistan, a recent suicide blast in Uruzghan province and the deadly bombing at the Indian embassy in Kabul.

Karzai's ministers warned that unless Pakistan's leaders verifiably [rein in] the spy agency, upcoming talks scheduled between the two countries on assistance along the border region and economic cooperation will be postponed.

The Afghan allegations appear to have more traction in the wake of a report published last month by the RAND Corp, a US-based think tank, and funded by the US Defense Department. According to CNN, the report states that the ISI has been training and supporting insurgents in Afghanistan.

The study, "Counterinsurgency in Afghanistan," found that some active and former officials in Pakistan's intelligence service and the Frontier Corps – a Pakistani paramilitary force deployed along the Afghan border – provided direct assistance to Taliban militants and helped secure medical care for wounded fighters.

It said NATO officials have uncovered several instances of Pakistani intelligence agents providing information to Taliban fighters, even "tipping off Taliban forces about the location and movement of Afghan and coalition forces, which undermined several U.S. and NATO anti-Taliban military operations."

Pakistan is facing the heat on many diplomatic fronts. In the wake of the attack on the Indian Embassy in Kabul, a meeting of the heads of the federal investigation agencies of India and Pakistan scheduled for this week has been canceled, according to Dawn, the leading Pakistani English-language daily.

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