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Peyton Manning is back and other NFL Week 1 highlights (+video)

Peyton Manning led the Denver Broncos to victory over Pittsburgh. Rookie Robert Griffin III threw for 320 yards for a Redskins win. The San Francisco 49ers schooled Aaron Rodgers and the Green Bay Packers.

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The Falcons took advantage of a Chiefs defense missing four starters. Pro Bowl linebacker Tamba Hali was suspended for an unspecified violation of the league's substance-abuse policy, and three others were injured.

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Kansas City matched Atlanta most of the first half, trailing 20-17 at the break. But a missed field goal by Ryan Succop early in the third quarter proved to be the turning point.

Matt Cassel finished with 258 yards passing for Kansas City, but also threw two interceptions and lost a fumble.

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Buccaneers 16, Panthers 10

TAMPA, Florida (AP) — Tampa Bay's rejuvenated defense came up with two interceptions against Cam Newton and the Buccaneers won their debut under coach Greg Schiano.

Josh Freeman threw a 6-yard touchdown pass to Mike Williams and Connor Barth kicked three field goals to help the Bucs stop a 10-game losing streak that prompted the firing of former coach Raheem Morris. Schiano came the Tampa after spent the past 11 seasons transforming Rutgers from one of the losingest programs in college football into a Big East contender.

Newton threw for 303 yards and one touchdown.

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Cardinals 20, Seahawks 16

GLENDALE, Arizona (AP) — Kevin Kolb replaced injured John Skelton and led Arizona on the deciding touchdown drive, throwing 6 yards to Andre Roberts for a score with 4:59 to play.

Aided by two pass interference penalties, Seattle drove to the Arizona 4 in the final seconds. But rookie Russell Wilson threw three straight incompletions and the Cardinals held on.

Adding to the confusion, Seattle appeared to have called a timeout when it had none remaining, but that turned out to be a mistake by the replacement officials working the game.

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Copyright 2012 The Associated Press.

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