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Peyton Manning is back and other NFL Week 1 highlights (+video)

Peyton Manning led the Denver Broncos to victory over Pittsburgh. Rookie Robert Griffin III threw for 320 yards for a Redskins win. The San Francisco 49ers schooled Aaron Rodgers and the Green Bay Packers.

By StaffAssociated Press / September 10, 2012

Denver Broncos quarterback Peyton Manning at the start of an NFL football game between the Denver Broncos and the Pittsburgh Steelers at Sports Authority Field at Mile High, Sunday, Sept. 9, 2012 in Denver. Denver won 31-19.

(AP Photo/David Zalubowski)

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Denver

Broncos 31, Steelers 19

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Peyton Manning made a successful return from a year's sabbatical, leading the Broncos past the Steelers. The four-time MVP coming off four neck surgeries completed 19 of 26 passes for 253 yards and two touchdowns.

He got a big assist from another free agent, cornerback Tracy Porter, whose 43-yard interception return of a Ben Roethlisberger pass with 2 minutes left sealed the win.

Manning, jettisoned by the Indianapolis Colts in March after missing all of last season with a nerve injury that weakened his throwing arm, hit Demaryius Thomas with a 71-yard touchdown toss for his first as a Bronco. It was his 400th career TD toss.

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49ers 30, Packers 22

GEEN BAY, Wisconsin (AP) — San Francisco's defense smothered Aaron Rodgers and the Green Bay offense for most of the game, then made one last stand to stop a late rally.

The Packers rallied from a 16-point deficit in the fourth quarter, and pulled within eight points when Aaron Rodgers threw a touchdown pass to James Jones with 6:05 left, but the 49ers defense held the Packers in the final minute to come away with a big win to open the season.

Randall Cobb's 75-yard punt return for a touchdown and a 2-point conversion early in the fourth quarter cut the 49ers lead to 23-15. But Rodgers threw an interception to linebacker NaVorro Bowman and Frank Gore ran for a 23-yard touchdown.

David Akers tied an NFL record when he kicked a 63-yard field goal to the end the first half, with the ball bouncing off the crossbar and going through the uprights.

Redskins 40, Saints 32

NEW ORLEANS (AP) — Robert Griffin III began his NFL career by connecting on 19 of 26 passes for 320 yards and two touchdowns, and the Washington Redskins handed the Saints a 40-32 loss in their first game since the bounty scandal that overshadowed New Orleans' offseason.

Griffin completed his first eight passes, including an 88-yard touchdown pass to Pierre Garcon, tying for the second-longest scoring pass by a quarterback making his NFL debut.

Rookie running back Alfred Morris rushed for 96 yards and two touchdowns. Aldrick Robinson, making his NFL debut, had a touchdown catch among four receptions for 52 yards.

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