There are no reports of damage, injuries or power outages linked to the temblor.
"All is calm in the city of Los Angeles," Los Angeles Fire Department Capt. Steve Ruda said.
Nearly an hour after the quake, the California Highway Patrol got reports of a buckled 10-foot stretch of concrete in a center lane of southbound Interstate 5 south of downtown in the Downey area.
CHP Officer Daniel Asleson said later the quake probably didn't cause the buckling. Damage was reported a day earlier in the lane, which is heavily used by big-rigs.
California Department of Transportation crews temporarily patched the area again early Tuesday and the lane reopened an hour later. Work on a permanent fix begins Tuesday night.
"The earthquake probably did contribute to it, a little bit, but ... it's normal wear and tear," Asleson said.
The magnitude-4.4 quake, centered about 10 miles east of downtown Los Angeles, struck shortly after 4 a.m., according to the U.S. Geological Survey.
Deputies were immediately dispatched to make "critical facility checks — bridges and dams, stuff like that," the sergeant said.
Though the quake was considered small in size, it was felt over a large swath of Southern California.
"The building started shaking. That's it. I'm used to it," downtown security guard Ruben Solis, 25, said from his booth in the high-rise district. Solis said he checked his monitors and no alarms were triggered. "I got up and went on patrol."
But fellow security guard Nonie Bailey, 55, was on the fourth floor and headed quickly for the ground level.
"It shook real hard. I thought the building was coming down. I was on the fourth floor and I got down to the ground," Bailey said.
"All our battalions reported a Level 1, meaning they felt it but there was no damage," Gougis said. He said the quake was felt at his east Los Angeles headquarters.
"There was an initial jolt, then mild shaking after that," he said.
The quake hit not far from the 1987 Whittier Narrows earthquake, a magnitude 5.9 quake that killed eight people and caused more than $350 million in damage.
The latest jolt is too small to inflict the same damage.
"I'm sure people would have felt it, but this is not an earthquake that will be damaging," said USGS geophysicist Amy Vaughan.
Tuesday's early morning jolt was probably not related to the Whittier Narrows quake because too much time has elapsed, said California Institute of Technology seismologist Kate Hutton.
Scientists have not yet determined which fault was responsible for the latest quake.
Hutton said there's a small chance that Tuesday's temblor is a precursor to a larger event, but the likelihood diminishes over time.