Bilateral issues. Perhaps most pressing is the Reagan administration's decision last month to expel 25 Soviet diplomats at the United Nations who were allegedly engaged in espionage. All 25 were to have left by Oct. 1, but after Soviet protests and high-level negotiations in the Daniloff case, the US said the 11 remaining diplomats would not have to leave until Oct. 15. Human rights. US Secretary of State Shultz says Jewish emigration is ``right up at the top'' of the US agenda for Reykjavik. ``We will never give up on this issue,'' Mr. Shultz says. Jewish activists say 370,000 Jews are being denied permission to leave; US officials say emigration is at a historic low. Afghanistan. The presence of an estimated 115,000 to 120,000 Soviet troops in Afghanistan is likely to be brought up by the US. For nearly seven years, Soviet troops in Afghanistan have been battling Afghan resistance fighters for control of the country. Gorbachev announced in July that the Soviets would withdraw six regiments (about 6,000 men) before 1986 ended; the pullout is slated for Oct. 15. But US officials have voiced skepticism, saying that fresh Soviet troops are, in fact, being sent in. The Middle East. The Soviet Union is eager to widen its role in a region where it has close but still shaky ties with only two states -- Syria and Libya. Moscow has proposed an ``international conference'' for negotiating Arab-Israeli peace. This call has been echoed by Arab and Palestinian leaders, but the US and Israel are not keen to involve the Soviets. Both say Moscow must first reestablish diplomatic ties with Israel and lift restrictions on emigration of Soviet Jews. Angola. The Soviets give military aid to Marxist Angola and back an estimated 30,000 Cuban troops there to help the government fight an insurgency. Moscow says it supports Angola, in part, to protect it from South African aggression. The Soviets see Pretoria as the real power behind Angola's rebels known by the acronym Unita. The Reagan administration says it wants the Cubans out of Angola. The Angolan government says before Cuban troops can be sent home, the South Africans must end their illegal occupation of neighboring Namibia (South West Africa). Neither side is willing to go first. This year, the US reversed a 10-year ban on aid to Angolan factions and began delivery of $15 million in aid to the rebels. Nicaragua. The Reagan administration opposes Nicaragua's ties with the Soviets -- especially those with Moscow's ally, Cuba -- and says that more than $600 million in Soviet military aid is going to the ruling Sandinistas. Reagan has charged that Nicaragua is trying to export revolution to other Central American countries and is supplying arms to rebels in El Salvador. Since 1981, the CIA has funneled millions of dollars to the Nicaraguan contra rebels. Cambodia. Since 1979, when the Khmer Rouge fell from power, Cambodians have been fighting Soviet client Vietnam and the Vietnamese-backed government in Phnom Penh for control of their country. Besides its objections to Vietnam's presence, the Reagan administration also sees Cambodia as part of a larger regional threat: Soviet military expansion in Southeast Asia.