A group of Turkish ultra-nationalists attacked three US sailors on a crowded street in Istanbul on Wednesday, shouting "Yankee go home" and trying to pull hoods over their heads in an assault condemned by the United States.
Video footage posted on the website of the ultra-nationalist Turkish Youth Union showed the attackers surrounding the sailors, calling them "murderers" and throwing orange paint at the men.
The attackers' actions were an apparent reference to an incident in Iraq in July 2003, when US forces detained a Turkish special forces unit, leading its members away for interrogation with hoods over their heads.
"Because we define you as murderers, as killers, we want you to get out of our land," one of the attackers said in English, before the group chased the soldiers down a street lining the Bosphorus on the edge of Istanbul's historic peninsula.
The US embassy described the video, apparently filmed by one of the gang, as "appalling" and condemned the attack.
"(We) have no doubt the vast majority of Turks would join us in rejecting an action that so disrespects Turkey's reputation for hospitality," it said in a statement on its Twitter account.
Colonel Steve Warren, a Pentagon spokesman, said it appeared to be a one-off incident carried "by some local thugs."
"We're working closely with Turkish authorities to have this investigated and to get to the bottom of exactly what happened," Warren said, condemning what he described as an "ugly, disturbing" attack.
Officials said the three sailors were unharmed and back aboard the US Navy guided-missile destroyer, USS Ross. Shore leave had been canceled for other US sailors from the ship and the Ross was expected to leave Istanbul on Thursday.
"We enjoy a strong relationship with our NATO ally. We don't see this as something that will disrupt that strong relationship," Warren said.
Turkey has long been one of Washington's key allies in the Middle East and is a member of the NATO military alliance, but anti-American sentiment runs deep in parts of society, particularly since the 2003 US-led invasion of Iraq.
A poll by the Pew Research group released at the end of October showed only 19 percent of Turks had a favorable view of the United States.