A fire erupted Friday morning at General Electric's Appliance Park in Louisville, Kentucky, shutting down production at the sprawling manufacturing center that employs thousands.
The fire broke out in a non-production building, creating huge columns of smoke as more than 100 firefighters battle the blaze.
GE spokeswoman Kim Freeman says there are no known injuries.
She says the building engulfed in flames was used for offices and storage, and is also used by a private supplier distribution center.
News media reports say the cause is not yet known.
Freeman says production has ceased while firefighters battle the blaze.
GE makes a range of appliances at the facility, including washing machines, dryers, dish washers, refrigerators and water heaters.