This guide is designed to alert readers to the scope and variety of programming coming up. Listing is not meant to represent blanket endorsement. Viewers are urged to be selective. TONIGHT Presidential debate (ABC, CBS, NBC, PBS, CNN, 9-10:30 p.m., E.T.: Please check local listings): The second and final Bush-Dukakis confrontation - live from the University of California in Los Angeles - is expected to have the same format: question, answer, brief rebuttal.

FRIDAY Back on the Road With Charles Kuralt (CBS, 8-9 p.m.): Here's a collection of vignettes - often inspiring ones - by Mr. Kuralt as he samples America's byways and people, like the widow from a small mill town who spends her life cooking meals for anyone who comes to her door.

SATURDAY World Series (Please see tomorrow's sports page for TV schedule). All-Star Celebration: the '88 Vote (ABC, 9-11 p.m.): A long list of celebrities in many fields - from William F. Buckley Jr. to Whoopi Goldberg - appear in this comedy-music special aimed both at laughs and at getting people to vote.

SUNDAY America Picks the All-Time Favorite Movies (ABC, 8-9 p.m.): Jerry Lewis hosts a special with an unusual format: Viewers can phone in votes for films they liked best in several categories. Out of Africa (CBS, 9-11 p.m.): The 1985 movie - starring Robert Redford and Meryl Streep - of Danish writer Isak Dinesen's memoirs was filmed on location in Nairobi. It airs in two parts (Part 2: Monday). Masterpiece Theatre (PBS, 9-10 p.m.): The much-praised series begins its 18th season with the first of a seven-part story called ``A Perfect Spy,'' based on John leCarr'e's best-selling novel about the life of Magnus Pym, an elegant con man carrying on a family tradition.

MONDAY 60 Minutes: 20th Anniversary, the Second 10 Years (CBS, 8-9 p.m.): Second of a two-parter offering high points from the TV-history-making magazine news program. Out of Africa (CBS, 9-11 p.m.): Part 2 of the movie starring Robert Redford and Meryl Streep. Discover: The World of Science (PBS, 8-9 p.m.): The science-magazine series kicks off its fourth season of informatively fascinating shows, hosted by Peter Graves. Campaign: A View From Abroad (PBS, 9-10 p.m.): From several foreign sites - including the USSR and Japan - this program probes how the rest of the world views the American presidential race.

TUESDAY The American Experience (PBS, 9-10 p.m.): ``Indians, Outlaws, and Angie Debo.'' Who's the late Angie Debo? An early champion of the American Indian, who recounts her life in Oklahoma.

Schedules may vary in some time zones. Please check local listings, especially for PBS, where individual stations often air programs on differing days and times.

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