The US is expected to call for Bashar al-Assad to step down and UN Secretary-General Ban Ki-Moon will push for International Criminal Court action against the Syrian president.
Turkey, which is leading an international effort to persuade the Assad regime against violence, last week gave Syria a deadline of 10 to 15 days to stop its brutal crackdown.
Crackdowns on the scale of Syria's have prompted action by the International Criminal Court elsewhere. The ICC opened an investigation against Qaddafi just three weeks into Libya's uprising.
As the death count rises in Syria, calls are mounting for President Obama to denounce Syria's President Bashar al-Assad. But Syria's pivotal role in the region and fragile ethnic and religious balance are complicating the situation.
Secretary of State Hillary Clinton sought to bolster America's largely symbolic sanctions. But while Syrian allies such as Russia have lobbied hard for reforms, few appear eager to apply sanctions.