On Thursday he named George Mitchell as a special envoy, and he has already signaled that the US will reengage the region.
The President-elect is likely to rely on Republicans as well as Democrats to advise him and carry out policy.
Radovan Karadzic appears Friday to answer to charges of war crimes in the 1990s.
Moscow has gained leverage, threatened Georgia's pro-West leader, and bolstered national pride.
The Bosnian Serb leader, indicted by the UN war crimes tribunal on 15 counts including genocide, had been on the run for 13 years.