At least 42 people were being treated for injuries, with some rushed to the hospital, a city health official said on condition of anonymity because he was not authorized to brief reporters.
With the Islamist constitution backed by President Mohamed Morsi looking likely to pass this weekend's referendum, the opposition is looking to push amendments next year.
If President Bashar al-Assad falls and the disparate Syrian opposition groups lose their common enemy, their ranks will likely fracture – perhaps violently.
Since street protests began last year, Jordanians have warily eyed the southern towns that make up the regime's loyalty base. Residents there remain divided over where they stand on reform.
Egypt's public prosecutor quit under pressure from his opponents in the judiciary, drawing an angry response from the Muslim Brotherhood ahead of a second round vote on a divisive draft-constitution.
The party tied to President Mohamed Morsi says that nearly 57 percent of voters supported the new constitution, while about 43 percent voted against it. A second vote comes later this week.
As Egyptians vote today in a referendum on a controversial draft constitution, the debate is dominated by President Mohamed Morsi's actions, not the document.
The proposed charter is largely supported by Islamist parties, while opposition groups accuse it of being a power grab for the Muslim Brotherhood.
At least 19 people were reported injured in the violence in Alexandria, which broke out after an ultraconservative cleric urged worshippers to vote 'yes' and described the opposition as 'followers of infidels.'
President Mohamed Morsi's reliance on Muslim Brotherhood activists to put down protests around the palace has further alienated some Egyptians from his rule.