49ers QB Colin Kaepernick and linebacker Aldon Smith teamed up to vanquish the Chicago Bears on Monday Night Football. Colin Kaepernick, in his first NFL start, passed for 243 yards and two touchdowns.
Peyton Manning led the Denver Broncos to victory over Pittsburgh. Rookie Robert Griffin III threw for 320 yards for a Redskins win. The San Francisco 49ers schooled Aaron Rodgers and the Green Bay Packers.