Already, businesses in Iran are pre-positioning themselves for the opportunities that could line up after a possible lifting of sanctions if an agreement is met on its nuclear program.
Both President Obama and Secretary of State Kerry hit positive notes in their messages. But Iran's Supreme Leader Khamenei was critical of other elements.
Israeli Defense Minister Moshe Yaalon says Israel is on its own in facing the threat from Iran. Previously, he opposed a unilateral Israeli strike.
Iran has assured skeptical diplomats that it is slowing its nuclear work. The latest report from the UN nuclear agency backs them up.
The US and Iran have attacked each other in public to sell nuclear talks to skeptical audiences at home. But harsh words have eroded trust.