

Television talk-show host Oprah Winfrey relaxes in her studio office following a morning broadcast in Chicago. Winfrey came to Chicago in 1984 to WLS-TV's morning talk show, 'A.M. Chicago.' A month later the show was No. 1 in the market. A year later it was renamed 'The Oprah Winfrey Show.' Charlie Knoblock/AP/File
On Saturday Night Live, actress Joan Cusack plays the owner, and Oprah Winfrey plays the police officer, during 'The Cute Shop' skit in 1986. Alan Singer/NBCU Photo Bank/AP/File
Oprah Winfrey shows off her new figure during the taping of her show in Chicago, after she lost 67 pounds following a liquid diet and exercise, in 1988. Charles Bennett/AP/File
The 1989 issue of TV guide, featuring Oprah Winfrey's face superimposed on actress Ann-Margret's classic hourglass figure. The illustration was not identified as a composite. AP
Oprah Winfrey shows off the Chicago Bulls jersey given to her by Dennis Rodman after a playoff game with the New York Knicks in Chicago, in 1996. Fred Jewell/AP/File
Oprah Winfrey leaves the federal courthouse after jury selection in Amarillo, Texas, in January 1998. A jury of eight women and four men was selected in the multi-million-dollar defamation case pitting Texas cattlemen against the talk-show queen. Oprah won the case. Eric Gay/AP/File
Saturday Night Live's Will Ferrell as Dr. Phil McGraw, and Maya Rudolph as Oprah Winfrey, during an 'Oprah' skit in 2000. Mary Ellen Matthews/NBCU Photo/AP/File
Democratic presidential candidate Vice President Al Gore does a high-five with talk show host Oprah Winfrey during the taping of 'The Oprah Winfrey Show' in 2000. George Burns/Harpo Productions/AP/File
Oprah Winfrey and Irish rocker Bono walk down Chicago's 'Magnificent Mile' for a shopping spree to promote his new Red product line in 2006. M. Spencer Green/AP/File
Oprah and students are seen during the opening of the Oprah Winfrey Leadership Academy for Girls in the small town of Henley-on-Klip, South Africa, in 2007. Winfrey opened a school for disadvantaged girls, fulfilling a promise she made to former President Nelson Mandela six years before. Denis Farrell/AP/File
Democratic presidential candidate, Senator Barack Obama, greets entertainer and talk show host Oprah Winfrey at a rally in Des Moines, Iowa, in 2007. Oprah went on to endorse Obama for president. Ramin Rahimian/Reuters
Oprah Winfrey (c), enters Wallace Wade Stadium at Duke University, in Durham, N.C., where she was the graduation keynote speaker in 2009. John Rottet/The News and Observer/AP
Oprah Winfrey sings the National Anthem, as Paul McCartney listens, at the Kennedy Center on December 5, 2010. Winfrey and McCartney were amongst the recipients for the 33rd annual Kennedy Center honors.
Poet Maya Angelou and Oprah Winfrey, share a laugh during a star-studded double-taping of "Surprise Oprah! A Farewell Spectacular," May 17, 2011, in Chicago. "The Oprah Winfrey Show" is ending its run May 25, after 25 years. Charles Rex Arbogast/AP
Showing "Oprah" painted on her head, Victoria King, waits for the taping of The Oprah Winfrey Show May 18, 2011 at the United Center in Chicago. Charles Rex Arbogast/AP
Stevie Wonder (l) performs for Oprah Winfrey, as Jamie Foxx looks on during a star-studded double-taping of "Surprise Oprah! A Farewell Spectacular," Tuesday May 18, 2011 in Chicago. Charles Rex Arbogast/AP
Gayle King (l) and Maria Shriver hug Oprah Winfrey during a star-studded double-taping of "Surprise Oprah! A Farewell Spectacular," Tuesday May 18, 2011 in Chicago. Charles Rex Arbogast/AP